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Despite their effectiveness, these drugs have been linked to severe gastrointestinal complications and other potential risks, underscoring the importance of fully understanding their effects

International journal of molecular sciences 2023;24

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Serious hypersensitivity reactions including anaphylaxis and angioedema have been reported with RYBELSUS Warnings and Precautions Risk of Thyroid C-Cell Tumors: Patients should be further evaluated if serum calcitonin is measured and found to be elevated or thyroid nodules are noted on physical examination or neck imaging Acute Pancreatitis: Acute pancreatitis, including fatal and non-fatal hemorrhagic or necrotizing pancreatitis, has been observed in patients treated with GLP-1 receptor agonists, including RYBELSUS

However, clinical data relating to the potential of these drugs to improve bone health is only now beginning to emerge