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1) The group level BEN difference between the smokers and the controls was assessed with the massive univariate two-sample t-test implemented in SPM8 using the spatially normalized BEN maps

According to U.S

There are more than 7,000 chemical components found in cigarette smoke and hundreds of them are harmful to human health, according to the Centers for Disease Control and Prevention

With the increase of oxalic acid content, the SHAP value also gradually increased, and the model was more tended to classify tobacco leaves as upper leaves