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As bedaquiline mainly undergoes phase one reactions catalysed by CYP3A4, its exposure may be either reduced or increased during co-administration with inducers or inhibitors of CYP3A4 respectively (Sirturo, 2012)

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182 Concerning the Prohibition and Immediate Elimination of the Worst Forms of Child Labor (Worst Forms of Child Labor Convention), ratified by the United States in 1999, prohibits slavery or slave-like practices, child pornography and prostitution, illicit activities, including drug trafficking, as well as the employment of children under the age of 18 in work which, by its nature or the circumstances in which it is carried out, is likely to harm the health, safety or morals of children (also known as hazardous work).[277] As a state party to the Worst Forms of Child Labor Convention, the United States is obligated to take immediate and effective steps to ascertain what forms and conditions of child labor in agriculture violate the convention and then eliminate them.[278] The Convention obliges member states to take immediate action to prevent children from engaging in the worst forms of child labor
