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[DOI] [PubMed] [Google Scholar] 107.McElwee J.J., Schuster E., Blanc E., Piper M.D., Thomas J.H., Patel D.S., Selman C., Withers D.J., Thornton J.M., Partridge L., Gems D

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Table 61 Xenobiotic Metabolizing Enzymes The phase 1 enzymes lead to the introduction of functional groups such as OH, COOH, SH, O, or NH 2

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[1] Because intrinsic-factor-dependent uptake in the distal ileum can be absent in conditions such as autoimmune gastritis, pancreatic insufficiency, or bariatric surgery, the intramuscular or subcutaneous route bypasses gastrointestinal barriers and reliably restores serum concentrations
