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Addict Biol 7(1):7576 World Health Organization (2013) Review of areca (betel) nut and tobacco use in the Pacific: a technical report World Health Organization (2019) WHO global report on trends in prevalence of tobacco use 20002025 Yang H, Ma C, Zhao M, Magnussen CG, Xi B (2022) Prevalence and trend of smokeless tobacco use and its associated factors among adolescents aged 1216 years in 138 countries/territories, 19992019

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Consistent with this idea, nadir CD4+ count is a factor that predicts cognitive impairment in PLWH [73] and modifies ART magnitude effects on cognitive outcomes [74]

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