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[26] on the other hand, only examined current e-cigarette use, without accounting for prior smoking history: had there been a significant association between e-cigarette use and onset of respiratory symptoms, it could be due to prior cigarette smoking, in which case adjusting for pack-years would be necessary (though not necessarily sufficient) to account for this [14]

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This step is crucial to preserving the plants beneficial properties

Code availability The Python, perl, and R scripts used to calculate coefficient, merge multiple clusters, construct gene-metabolite regulatory network and visualization are publicly accessible on GitHub ( A permanent version of all code is available at Zenodo ( 138

Denny CH, Holtzman D, Cobb N: Surveillance for health behaviors of American Indians and Alaska Natives

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