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In addition, oxidative stress also activates vascular smooth cells by promoting their proliferation and migration, which plays a crucial role in vascular calcification and remodeling [102]

Maxwell SR, Thomason H, Sandler D, LeGuen C, Baxter MA, Thorpe GH, et al

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13 This reality is indicative of the potent toxicity of tobacco smoke inhaled by smokers for decades, says the Thoracic Surgery Clinics journal
