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Acupuncture on obesity: clinical evidence and possible neuroendocrine mechanisms

However, the interest in GLP-1 goes beyond celebrity endorsements

Gonadal steroids can also influence GLP-1R expression in the brain and other tissuesin the whole hypothalamus, for example, the highest GLP-1R expression is found in the late proestrus stage (46), providing further mechanistic support for potentially higher sensitivity to GLP-1 effects during this phase of the cycle (33, 47)

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Wegovy is an injection administered once weekly and contains higher doses than its Ozempic counterpart