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Doctors can use nicotine tests to measure levels of nicotine and its byproducts in a persons: urine blood saliva hair nails When a doctor is testing for tobacco use or exposure to nicotine, they will likely test for cotinine
doi: 10.1289/ehp.01109579
A 1995 study published in medical literature found that nicotine gum had no significant impact on rectal sensation in ex-smokers
