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In 1999, the Justice Department filed a lawsuit against the countrys largest cigarette manufacturers and tobacco trade organizations, claiming civil fraud and racketeering violations over the course of more than 50 years

The APPH tests diminishing relevance over time suggests moving from a harm-reduction framework to a consumer-protection framework

A doctor can make a diagnosis and recommend the best treatment

Smoking might counteract the effects of some types of antipsychotic medication, which could result in a need for increased medication dosage to achieve the targeted effect (Winterer, 2010)

PMID 16946095

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