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The same RM-ANCOVA model with HuynhFeldt corrections indicated that the difference in E2 profiles between exposed to smoke (SM) versus unexposed group (nSM) did not vary throughout days of menstrual cycle, as shown by the nonsignificant Total Smoke Exposure groups time interaction term (within-subject test, F 17,1836 = 1.35, p = 0.18, with HF correction)

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Researchers experimented on laboratory rats in settings designed to mimic the secondhand smoke exposures that humans experience, and found that the chemical components of tobacco smoke impact fetal brain development in all stages of pregnancy

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