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Menthol, a chemical compound found in peppermint, reduces the harshness of cigarette smoke and the irritation from nicotine, making it easier to inhale and potentially increasing nicotine addiction

Thats about 600mg total nicotine Absorption gives you about 240mg to 300mg Divide that by ~20mg per cigarette pack = 12 to 15 packs of cigarettes So yeah one 5000 puff vape can contain the nicotine equivalent of 1215 packs of smokes

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Smoking also upregulated pathways related to amino acid and nucleotide sugar metabolism

The study was published in the journal Addiction

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