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In addition to SGLT2 inhibitors and GLP-1 receptor agonists, finerenone, a nonsteroidal mineralocorticoid receptor antagonist, has demonstrated significant cardiovascular and kidney-protective effects in people with type 2 diabetes mellitus and CKD or HF [129-132]

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In a clarifying statement, the FDA confirmed with the drugs manufacturer, Eli Lilly and Company, that the companys production capacity is now sufficient to meet current and anticipated national demand

caution is needed for patients with a history of medullary thyroid cancer

10.1073/pnas.84.20.7005
