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Acknowledgments The authors would like to thank the authorities in Mashhad University of Medical Sciences and in School of Pharmacy (MUMS) for their supports

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Under its contract with H&V, Lorillard assumed sole responsibility for any harmful effects. It launched Kent at a press conference at New Yorks Waldorf-Astoria, touting the Micronite filter as the greatest health protection in cigarette history. Playing on the publics gee-whiz faith in science and technology, Kent ads told a glamorous, if vague, back story of how the quest for a new filter ended in an atomic energy plant, where the makers of KENT found a material being used to filter air of microscopic impurities. What is Micronite? another ad asked