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The APPswe/Ind (J20) mouse, which has two mutations in the human APP gene, was modified further to make a third mutation by replacing Met631 by leucine (M631L) in the APP gene, which corresponded to replacing Met35 of A42 with Leu
Marker proteins were obtained from Thermo Scientific (26616, Pager ruler)
Dysregulation of the HPA axis is a well-established feature of depression, and the interplay between stress, alcohol use, and mood disorders underscores the need for a comprehensive understanding of these mechanisms (Stephens and Wand 2012)
Recently, a widespread belief has emerged that Vitamin B12 causes weight gain
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