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Keywords: optic neuropathy, tobacco, alcohol, toxins, visual field Introduction Nutritional and toxic optic neuropathies (NTON) represent a group of medical disorders defined by visual disturbances due to optic nerve damage by a nutritional deficit or a toxin

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It is their duty, to throw off such Government only in extraordinary conditions after a long train of abuses and usurpations, design[ed] to reduce them under absolute Despotism. But since mankind are more disposed to suffer, while evils are sufferable, the Declaration also intends to convince those not eager for war to anticipate greater injustices if King George is not stopped

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PMID 11717374

This is also used by your dentist many use local anaesthetics include phenylephrine (a noradrenaline analogue) to keep the anaesthetic local (thanks, Malcom from comments section!)