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It can also occur after stopping long-term corticosteroid treatment too quickly

Can freedom from smoking be achieved in patients with pain

It's both a dramatic turn...literal and meta stop." The explain xkcd website is a wiki solely dedicated to explaining each and every joke and reference in the xkcd webcomic (xkcd can be very esoteric at times, with jokes often involving specific scientific knowledge and/or obscure references, so most readers can expect to find multiple comics that they don't understand)

she wore these long lace gloves, fashionable back home

Specifically, premature ageing and skin atrophy. Studies into smoking and skin ageing actually date back to the early 1970s

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