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However, heavy machine-rolled cigarette smokers had a statistically significant increased risk of hypertension compared with non-smokers, and a J-shape association has been found between the average daily consumption of machine-rolled cigarettes and the risk of hypertension

Selection of the reviews was made independently by two of the authors, and any conflict was resolved by deliberation with the third author

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Smoking also weakens the immune system, creating more likelihood of getting sick and staying sick longer

This has been done in many countries including Brazil and there are lessons that can be borrowed by Malawi, he observes