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doi:10.1002/anie.200900231 Return to citation in text: [1] Soto, C

With regard to the molecular toxic mechanisms of tobacco, oxidative stress or inflammasome activation as well as a chronic activation of aryl hydrocarbon receptor signaling can contribute to premature aging and the development of neoplasms by affecting metabolism, extracellular matrix remodeling, inflammation, pigmentation, DNA repair, and apoptosis 10

We support retailers with proof-of-age schemes and awareness training and engage with governments and call for minimum age laws if none already exist

the sharp sucking in, the delayed exhale for emphasis