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Cigarette smoke (CS) contains a large number of toxic substances, can cause a series of changes in the trachea, lung tissue, pulmonary blood vessels, and promotes the occurrence and development of COPD

doi:10.1080/14622200802027214

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Health minister Dr James Reilly said: "Given all we know about the dangers of smoking, it is not acceptable to allow the tobacco industry to use deceptive marketing gimmicks to lure our children into this deadly addiction and to deceive current smokers about the impact of their addiction." He added that standardised packaging will "remove the final way for tobacco companies to promote their deadly product in Ireland"

Among many other topics, the Preventative Health Taskforce revisited the evidence and the status of policy internationally on graphic health warnings for tobacco products

Inoue ended the manga in the magazine in February 2016