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While the paper does not directly evaluate this, it potentially suggests that it is inattention and hyperactive/impulsive symptoms that drive the early take up of tobacco based products in young people with ADHD and that appropriate support to people with those ADHD symptoms (either through pharmacotherapy or other means) could ameliorate this. The paper is also noteworthy in the context of a recent British study, co-authored by Stott, which found people with ADHD have a much shorter life expectancy compared to the general population seven years shorter for men, and nine years shorter for women

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Thus, transgenic models of DQ8 and DR4, which recapitulate the shared epitope genetic risk allele, provide a valuable tool to investigate this interaction (33) exposed DR4 and DQ8 mice for 2 weeks prior to CII sensitization and continued for 10 weeks in the CIA model

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