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These differences were unexpected, especially because there are no notable differences in participant characteristics, and the trial implementation process was comparable across centers

Different types of tobacco leaf are selected, and then blended and processed with the other ingredients to create a cut tobacco mix

None of the currently available products deliver nicotine to the brain at a dose and rate similar to smoking

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To our knowledge, no prior study has shown that cigarette smokingboth continued smoking and new-onset smokingis associated with an increase in the likelihood of relapse to SUD among adults with past SUDs, the authors said