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Description
Nicotine affects exocrine glands leading to an initial stimulation of salivary and bronchial secretions and then followed by inhibition
And as lung tissue is damaged, it becomes more fibrous, making it harder for people to expand their lungs fully with each inhalation

ACM 60, 8490

Retrieved 11 February 2014

Urinary levels of cigarette smoke constituent metabolites are prospectively associated with lung cancer development in smokers

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