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Although cigarette smoke is very complex, consisting of over 4,000 compounds linked to CVD, most studies suggest that carbon monoxide, reactive oxygen species, and nicotine are responsible for the pathogenesis of smoking-induced cardiovascular disorders ( 10 , 11 )

Other Health Issues: Beyond cancer, tobacco use can cause gum disease, tooth loss, and a host of other health problems such as heart disease and respiratory issues

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Common misconception of e-cigarettes, 2010

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Abstract Background Nicotine dependence, factors associated with dependence, and self-reported side effects among people who use e-cigarettes are scarce in developing countries