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VD: Professor, Johns Hopkins University School of Medicine

doi: 10.1016/j.metabol.2020.154338

VERTIS CV Patients with atherosclerotic cardiovascular disease and T2DM were randomized to ertugliflozin 5mg (n=2752), 15mg (2747), or placebo (n=2747) and the primary composite outcome of cardiovascular death and non-fatal MI or stroke was determined after a mean duration of follow-up of 3.5 years (160)

Simultaneously, these medications suppress glucagon secretion from pancreatic alpha cells, reducing hepatic glucose production

This approach supports patients in achieving their goals while maintaining the structures that contribute to long-term health and confidence

[DOI] [PubMed] [Google Scholar] [31].Holzapfel BM, Reichert JC, Schantz J-T, Gbureck U, Rackwitz L, Nth U, Jakob F, Rudert M, Groll J, Hutmacher DW, How smart do biomaterials need to be