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The computational process followed three major steps: (i) retrieving data sets of known MAOIs from the literature and data sets of compounds identified and quantified in tobacco smoke, (ii) encoding the data sets using pharmacophore descriptor approaches, and (iii) calculating the pharmacophore similarities between known MAOIs and tobacco compounds from the data sets

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The smoke naturally becomes more full, robust, and satisfying the lower it burns, and they rarely require relighting

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E-cigarette companies also take advantage of other marketing outlets, including the internet, retail environments, and recreational venues and events

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