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In humans, some studies investigating acute and chronic exposure to e-cigarettes have identified adverse effects of ENDS use on vascular health, particularly in those with no history of prior combustible tobacco

[15] Tobacco taxes also produce significant improvements in public health, and arguments about alleged adverse economic effects of such taxes tend to be unsupported

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Reynolds Tobacco Company, Winston-Salem, N.C., U.S.A." in gold and navy lettering against green and tan ground, base of display

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