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Both showed a potential benefit for smoking cessation and high levels of continued e-cigarette use at the end of the intervention, but presented no long-term safety data, which aligns with the findings of our analysis.104 , 105 The patient engagement activities undertaken for this guideline to assess patient preferences included 19 individuals in phase 1 and 8 in phase 2, and were limited in terms of diversity, so may not be generalizable to the broader population

It is far from being a healthy solution for losing weight

For intermittent fasting, smoking may not contain enough calories to technically end the fast, yet it can still interfere with the health goals of fasting by affecting metabolism, increasing inflammation, and triggering hormonal responses

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PMI saw an increase from 145 registrations in 2024 to 206 registrations in 2025, a 42% increase