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[160] Nicotine is metabolized in the liver by cytochrome P450 enzymes (mostly CYP2A6, and also by CYP2B6) and FMO3, which selectively metabolizes ( S )-nicotine

Top Notes-Agar Wood, Cinnamon, Green Apple, Incense, Nutmeg, Pear, Saffron

Users can still get the buzz they crave from nicotine without the smell or residues associated with cigarette smoking

For more information on N-O-T, visit notforme.org The EX Program was developed by the Truth Initiative in collaboration with the Mayo Clinic Nicotine Dependence Center

The oral LD50 of nicotine in dogs is 9.2mg/kg 22

Co-users had higher education level and better income than tobacco only users