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Clinical trials assessing the efficacy of the nicotine patch for ST users in doses of 15-mg/day (Howard-Pitney et al., 1999) and 21-mg/day (Hatsukami et al., 2000) have failed to increase long-term ( 6 months) tobacco abstinence rates in ST users despite the fact that it has been shown to decrease craving and nicotine withdrawal symptoms
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