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To reduce the effect of bias, we adjusted observations that did not account for more than five confounders, including age and sex, because they were the significant bias covariates identified by the bias covariate selection algorithm 29 (Supplementary Table 7)

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14 Cigarette Smoking Covariates W5 smoke-related covariates included cigarette smoking status, pack years of cigarette smoking, secondhand smoke exposure, and number of cigarettes smoked per day

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Yes, as a communication tool

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