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These studies have used the adhesion of monocytic cells to human coronary endothelial cells as a surrogate pathophysiologically relevant event in atherogenesis (Poussin et al., 2016, 2020), 3D nasal epithelial culture models (Iskandar et al., 2017a), organotypic nasal epithelial tissue cultures (Iskandar et al., 2017c), organotypic oral epithelial tissue cultures (Zanetti et al., 2016), organotypic buccal epithelial tissue cultures (Iskandar et al., 2017c), organotypic bronchial epithelial tissue cultures (Iskandar et al., 2017b, 2017c), organotypic gingival epithelial tissue cultures (Zanetti et al., 2017), small airway epithelium models (Iskandar et al., 2017d) and aortic smooth muscle cells (Poussin et al., 2021)

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PMID: 31612218

Nicotine is also an addictive drug, though, and smokers characteristically display a strong tendency to relapse after having successfully stopped smoking for a time