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Cigarette smoke extract induces pyroptosis in human bronchial epithelial cells through the ROS/NLRP3/caspase-1 pathway

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About 2-3 mg of nicotine/kg of body weight may cause symptoms of poisoning, but a child may exhibit symptoms of nicotine poisoning after ingesting about 1 mg of nicotine/kg of body weight

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The ETH Zurich researchers now wanted to determine which guanines in the DNA the benzopyrene metabolites tend to alter, and in particular which of these changes also persist in the long term

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