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The surgeon general in 1964, Luther Terry, described the report's effect as a "bombshell." At the time, and for decades afterward, the tobacco industry tried to "poke holes" in research documenting the harms of smoking, Frieden says

Ive read almost all of Agatha Christies oeuvre and Miss Marple never, ever smoked

Risk of bias assessment was performed for each included study to evaluate the methodological quality and potential sources of bias

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Research on Smoking Exposure and Reflux Esophagitis Significant research examining the relationship between smoking and reflux esophagitis has found that current smokers are considerably more prone to develop this condition than those who have never smoked