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The temporal trend analysis (Figure 3) indicates that the burden of bladder cancer attributable to smoking has generally declined on a global scale, whereas no significant reduction has been observed in the US

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After an individual has smoked for some years, the avoidance of nicotine withdrawal symptoms and negative reinforcement become the key motivations to continue

Air pollution is one of the greatest threats to human health in the world and kills more people each year than tobacco, car accidents or diabetes

Once someone has started smoking that addiction makes it very hard to give up