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-OH-PdG and -OH-PdG are products of the reaction of acrolein with DNA while -OH-MePdG originates from reaction of crotonaldehyde with dG
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Less commonly, papules may be found on the wrist (Brown and Cook, 2020, Laing and Fleischer, 1991)

With regard to the aroma chemicals likely inhaled if present in herbal cigarettes, sesquiterpenes amounted to major components, viz., copaene, -muurolene, cubebol, -cadinene, nerolidol, germacrene d-4-ol, caryophyllene oxide, ledol, -eudesmol, and juniper camphor
