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BMI: U =368.5, Z =-.385, p =.700)

A recent meta-analysis found that the primary effects of e-cigarette use include an increased heart rate and elevated blood pressure [46]

A meta-analysis of 6 case-control studies (4209 malformed cases and 10,646 controls) published between 2000 and 2010 revealed that maternal smoking during pregnancy significantly increased the risk of cleft lip with or without cleft palate (OR 1.48, 95% CI 1.361.61) [25]

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