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Smoking during adolescence increases the risk of developing psychiatric disorders and cognitive impairment in later life (80, 81)

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The seminal plasma supports and protects spermatozoa from pathological levels of ROS through free radical scavengers such as ascorbate, alpha-tocopherol, uric acid, and ROS-metabolizing enzymes such as superoxide dismutase (against superoxide), catalase (against hydrogen peroxide), and glutathione peroxidase (against glutathione peroxide) [110]

In addition, the percentage of sperm tails increased with tyrosine-phosphorylated proteins and the number of rapid spermatozoa recuperated after an enrichment technique, suggesting that the transduction signals necessary for proper motility and capacitation were improved