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The BALF macrophages comprised ResAM and an Itgam + (CD11b) AM (AM Itgam + ) subset that expressed canonical macrophage markers ( Cd68 , Lyz2 , Adgre1 , Fcgr1 ) (37, 38) but lacked known ResAM markers ( Siglec1 + , Mrc1 + , Ear1 + , Fabp1 + , Itgam - ) (37) ( Figures 2CE )

Due to these unpleasant nicotine withdrawal symptoms, smokers often resume smoking

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