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Among the imported brands, cigarette pine contained the lowest amounts of nicotine and cigarette Winston contained the highest amounts of nicotine (14.40 mg)

Presbyterian Mixture combines sweet Virginias with choice Orientals and a touch of Latakia for a mellow, smoky, and complex all-day smoke

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PK/PD, pharmacokinetic/pharmacodynamic

For example, it is not technically straightforward to perturb off-target sites individually without affecting other closely related sites and, thus, difficult to derisk them