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Magnesium acts as a natural calcium channel blocker or antihypertensive medication

(2024) 30:e14489

To analyse the effect of hesperetin on PD, hesperetin was administered at a dose of 50 mg/kg bw for one week, and the results showed that hesperetin reduced oxidative stress by regulating NRF2, NF- B and mitochondrial apoptosis 224

Herbal modulation of P-glycoprotein

1000 mcg of Vitamin B12 daily for the first week , followed by 1000 mcg weekly for four weeks to restore proper levels.

Furthermore, in vivo xenograft transplantation of MHCC-97H cells have shown that number of pulmonary micrometastatic foci was significantly lowered in comparison to control group ( via inhibition of COX-2 and MMP-9, Ang-1, vasodilator-stimulated phosphoprotein (VASP) and VEGF (Noori-Daloii, 2012)
