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Triethyl citrate was more frequently found in refill fluids at elevated levels and ranged from 0.05 to 11.5 mg/mL (Table S3)

The human body can tolerate nicotine in small amounts, which is why smokers and vapers can use nicotine-containing products without immediate adverse effects

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The number of deaths caused by smoking is falling - but it remains the leading cause of preventable illness and premature death and is estimated to cause a quarter of all cancer deaths

Furthermore, as compared to non-smokers, cigarette smokers are known to show worse response to periodontal treatment 7,8

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