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Direct Myocardial Effects Although the presence of functional GLP-1 receptors on human ventricular cardiomyocytes remains a matter of debate, preclinical studies suggest potential direct cardioprotective effects

Pros and Cons of EAA Supplementation Advantages: - Low calorie content (about 60 calories per effective dose) - Rapid absorption and muscle protein synthesis stimulation - Non-satiating, so they can be added to meals without affecting appetite - Particularly effective for overcoming age-related anabolic resistance - Can be taken between meals or with lower-protein meals to boost their effectiveness Potential Drawbacks: - More expensive per gram of protein than whole food sources - Lack the additional nutrients (vitamins, minerals, fiber) found in whole foods - May have an unpleasant taste - Don't provide the satiety benefits of complete proteins Whole Food Protein Sources: The Foundation While EAA supplements can be valuable tools, whole food proteins should remain your foundation

Nat Immunol

The morning after, prioritize electrolyte-rich fluids before coffee or food

Effect of Weekly Subcutaneous Semaglutide vs Daily Liraglutide on Body Weight in Adults With Overweight or Obesity Without Diabetes: The STEP 8 Randomized Clinical Trial

With retatrutide and other multi-agonists on the horizon, we may soon see drugs that approach the effectiveness of bariatric surgery without the invasiveness