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[DOI] [PMC free article] [PubMed] [Google Scholar] 70.Gudkov A.V., Gurova K.V., Komarova E.A

Genes upregulated in smoke exposed tumors mapped to GO pathways related to: (1) negative T cell selection, (2) regulation of NK cell mediated immunity and (3) negative regulation of lymphocyte mediated immunity among others (Supplemental Table XX)

200 cigarettes
Mutations of KRAS (32%) and p53 (46%) are two of the most common gene mutations in LUAD and the co-occurrence of these two gene mutations is frequently observed [99]

Glutaminase 2, a novel p53 target gene regulating energy metabolism and antioxidant function

Li LY, Guan YD, Chen XS, Yang JM, Cheng Y
