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GLP-1 medications are contraindicated in patients with a personal or family history of medullary thyroid carcinoma or Multiple Endocrine Neoplasia syndrome type 2

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Structural differences between GLP-1 analogues and individual patient factors such as baseline gastric motility also influence tolerability

Lincoff presented the study findings in a late-breaking science session at the American Heart Associations Scientific Sessions 2023

Standardized uptake value (SUV) was calculated [SUV = radioactivity activity concentration (KBq/ml)/body weight (g)/injected dose (kBq)] for semi-quantitative analysis

Gastrointestinal adverse events were the most common side effects and were generally mild to moderate