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Since e-cigarette brands like Juul have only gained popularity over the course of the last decade, researchers have yet to determine their long-term health impacts

The long-term effects are complex, and research is ongoing, but one clearly documented risk of THC use in adolescence is in how the body handles fat, says Daniele Piomelli, a neuroscientist and leading cannabis researcher at the University of California at Irvine

2009 doi: 10.1016/j.jchromb.2010.12.012