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Metabolic stress increases

Shi R, Xu ZY, Xu XN, Jin JY, Zhao YN, Wang TM, et al

Furthermore, co-treatment with PDK inhibitors and erastin may synergistically enhance ferroptosis in cancer cells overexpressing GLUTs and xCT [18]

Nat Commun 16 , 2716 (2025)

Our new findings reveal an additional and unexpected function of this ligand-receptor pair, namely the guidance of Esm1 + ECs into the growing arterial vasculature