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After treatment for 3 months with ALA, the basal and peak diameter of the brachial artery was significantly increased in treated patients compared to placebo, demonstrating that ALA supplementation, by improving vascular tone, has a beneficial effect on cardiovascular health in overweight/obese young people

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Here are some symptoms of undermethylation to look out for: [22] Elevated homocysteine levels Depression Irritability Anxiety Multiple miscarriages Multiple chemical sensitivities Sensitivity to anesthetics Red face that lasts after exercising Allergies Being prone to addiction High libido Obsessive-compulsive disorder (OCD) Low pain threshold Headaches/migraines Digestive problems (such as IBS) Brain fog (especially after protein-rich meals) Insomnia High estrogen levels/estrogen dominance Low energy/fatigue Muscle pain Low levels of neurotransmitters (dopamine, norepinephrine, and serotonin) Heavy menstrual periods with blood clots Flakey skin rash under your nose* Lowered immunity* *Although I havent seen this in the research, its been an observation for me personally, as well as for a few clients, that difficulty fighting off viral infections as well as having a red rash under the nose, seems to correlate with poor methylation

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At Jacobson Cosmetic Surgery, dosing is individualized to help maximize comfort while supporting goals related to cellular recovery, cognitive support, recovery and performance, mitochondrial optimization, and healthy aging