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These neurogenic effects have been well documented due to the addictive properties of nicotine in the interference of dopamine pathways [17]

Nicotine is the primary addictive component in vapes, cigarettes, and tobacco products

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Although conflicting hypotheses on the potential role of nicotine in COVID19 pathology have recently been offered, we believe that nicotine itself, through its interaction with the nicotinic cholinergic system, as well as ACE2, may not only be of use in a variety of neuropsychiatric and neurodegenerative diseases, but may also be of potential use in COVID19