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However, it cannot be excluded that except for nicotine, chemicals like acrolein and methyl vinyl ketone, present in TS and e-cigs have been shown to cause oxidative stress by the generation of ROS through activation of protein kinase C via NADPH oxidase (Ott et al., 1998)

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Available online at: (Accessed June 6, 2020) 212 TheakstonJ

As social norms evolve, governments around the world have taken an increasingly hard line against cigarettes and other tobacco products